
Short-Chain versus Long-Chain Omega-3s: What’s the Difference?
Omega-3s exist in nature in two forms: short-chain and long-chain omega-3s. Short-chain omega-3s include alpha-linolenic acid. Alpha-linolenic acid is found primarily in plant-based food with the best sources being flaxseeds, walnuts, soybeans, canola oil, chia seed, and hemp. Short-chain omega-3s haven’t been proven, as of yet, to have the same health benefits as the long-chain fatty acids, DHA and EPA, that are anti-inflammatory and have benefits for heart and brain health. Long-chain fatty acids like DHA and EPA in their natural form are most abundant in fatty fish like wild salmon, mackerel and sardines. Some foods are also fortified with omega-3s but it’s in the form of short-chain omega-3s or alpha-linolenic acid.
The good news is alpha-linolenic acid can be converted to long-chain omega-3s. The problem is this conversion isn’t very efficient. In fact, the amount of dietary alpha-linolenic acid converted to DHA and EPA (the more beneficial long-chain fatty acids) is usually less than 10%. One study even showed that conversion was less than 0.1% in healthy males. Women appear to be slightly more efficient converters than men. This means you’re not getting a significant amount of the more beneficial long-chain omega-3s when you depend on plant-based omega-3 sources like flaxseed and walnuts. Not that these foods aren’t good for you, but the short-chain omega-3s they contain haven’t been as extensively studied as the long-chain omega-3s.
What Does This Mean?
Enjoy walnuts and flaxseed for their other health benefits. They’re a good source of fiber, and flaxseed has natural lignans that may offer protection against breast cancer. On the other hand, don’t count on them, or any other plant-based source of omega-3s, to provide the same cardioprotection as the long-chain omega-3s in fatty fish. The conversion is simply not efficient enough to give you the quantity you need. Also, don’t depend on products with added omega-3s to supply significant amounts of DHA and EPA. Again, these products are fortified with alpha-linolenic acid, plant-based omega-3s, which doesn’t yield significant amounts of DHA or EPA. Fatty fish is still your best source for long-chain omega-3s. If you choose to take fish oil capsules rather than eat fatty fish, choose a brand that’s molecularly distilled since this process removes virtually all of the heavy metals and other impurities that make some fish unhealthy.
References:
Men’s Health. “The Truth about Omega-3s”
Int. J. Vitam. Nutr. Res. 68 (3): 159–173.
American Journal of Clinical Nutrition 84 (1): 44–53.
