Before starting STS training, I never took a week off. But, I've never worked as hard as STS, except for Power Hour.
After Meso 1, I was begging for the week off. I enjoyed that week like it was the best vacation I'd ever had. LOL! My wife and I ran one day during that week off and did some abs. That was enough. I felt very strong for Meso 2. I really noticed a difference. Almost done with Meso 2. Looking forward to another week off, even though Meso 1 felt more brutal than Meso 2.