Well, I'm still completely traumatized by that cartoon "Up". I watched it with DH last week and if we even discuss it we start crying. It really ended ok and all, but the first few minutes basically ripped out my heart and then later on during a scene with a scrap book, I started bawling again. It was too much for my hormonal self.
Whoever mentioned 28 Days Later - Do you mean 28 Days? 28 Days Later is about man eating zombies which I guess could be kind of depressing.
It's one of my favorite movies though. I thought it was so well put together for a horror movie.