I never know when to keep my mouth shut, so here goes...
If you do any research, you'll realize that the issue at debate here is not actually botox, but the LD50 test, which is used to determine the toxicity of a chemical (not just Botox, but many chemicals). The LD50 is used to determine at what dose 50% of the animals tested die. It's a barbaric and highly unreliable test, but as it's cheaper than the alternatives available, many companies, including Allergen, the maker of Botox refuse to consider the alternatives. Science had proven time after time that toxicity that kills animals does not accurately transfer to humans. The 50, out of 100 animals that are killed during this testing (which is done for every batch of Botox created) do endure some horrific suffering before they die (the normal test period is 3-4 days - and any animal that is not dead is ethunanized at that point - but not before - no matter how badly they are suffering).
I understand that Botox is very helpful in many circumstances, but there are alternative testing methods available that are actually more reliable, however they are more costly. And if botox is being used strictly for cosmetic purposes, I personally feel that if one is an animal lover, one should avoid using botox until alternative methods are used. But that is a personal opinion. Others may think differently.
While I agree that going cruelty-free is impossible, I do feel that where cruelty can be eliminated it should be. It's too easy to say, "Oh well, that's the way things have always been done."