Could you describe your soreness? If it's what I think of as "normal" muscle soreness (kind of that tenderness that reminds you that you worked out), it's possible that you need to reevaluate your rest/active recovery time. I used to require only 24 hours after strength training, but I now do a strength day, cardio, strength, cardo, strength... followed by TWO active recovery days (normally do Tai Chi, longer stretch, a walking DVD, yoga, Classical Stretch/Essentrics, or something along those lines). You mentioned taking more days off, but I'm wondering if a different type of movement on those "off" days would help?
If it's DOMs... water with a sprinkle of salt and a squirt of lemon in it is my post workout drink when I'm expecting DOMs. I also like to go back and do one of Cathe's warmups at the end of a killer strength training workout, followed by the actual stretching to kind of dynamically stretch/move my body through full-range movements before adding that last stretch. And this is going to sound silly, but I start a load of laundry. lol My machines are in the basement, and I've found that going up and down the stairs a few times seem to help with DOMs (mine DOMS are always my butt/glutes). lol
I have vericose veins, and can't sit for long, so when I worked desk jobs where I had to sit, I'd get up and move around (go photocopy or file something) to get my circulation going.
If it's not DOM or "normal" exercise discomfort... you might want to see a doctor and ask for labs to be done. A nutritional deficiency can cause pain, cramps, numbness, muscle soreness, joint pain, and all sorts of things. That type of thing is usually easy to fix, once you've identified the deficit. As women, our bodies change a LOT and so do our needs (my body's needs completely changed for diet when I hit menopause, and I'm still learning what it needs for exercise). Hopefully all is well, and you just have a slight "tweak" to make to your exercise routine or diet.