IMO, most weight loss supplements might work in the short run, but they are full of ingredients that could harm you in the long run. Some contain stimulants that could be hard on the body. They might work for a while to get you to "look better," but possibly at the expense of being healthier.
There are healthier, natural alternatives to questionable supplements.
Aside from the basic "eat right and move," you can try the following:
To replace "appetite suppressant" supplements, buy some chia seed and make chia gel by soaking about 1/4 cup in 2 cups of water. Add the gel to smoothies, oatmeal, any liquid. It will add bulk and make you feel fuller without adding many calories. (Don't buy the chia sold for chia pets: it's coated with pesticides and is not meant to be eaten).
For 'stimulant' supplements, substitue a few cups of green tea throughout the day.
HTH!