When I started running again I was determined to do it without getting hurt. I realized that I had no idea how to run! A couple of things helped me...first I echo what everyone said here about easing into it...walk, stretch, walk, run, walk etc...
Second, I found a stretch that makes me look very weird, but works - I believe it is from Coach Scott Sonnon. You walk on the outside edges of your feet twenty or so paces or whatever it takes, then walk on the inside edges twenty or so paces (or whatever it takes), this amazingly relieves cramping and prevents shin splints.
Third, changing my foot strike. I use to heel strike. OUCH-Y. Now I can run painlessly for miles and miles and miles using ball-toe, or when walking using midfoot-ball-toe. (Hiitdog mentioned Chi running, which uses this foot strike, as does Prose Running...Prose also has a webpage on treadmill running which was useful.)
Finally, lifting weights/lower body exercises gave me all over tone and strength to avoid injury. There is an excercsie on Gym legs on the floor using the stability ball which helped too - I have to focus my attention to feel it - but I know this one exercise made a huge difference. It is the one where your resist the ball with hands while pulling the ball towards you with the toes.
I hope this helps your friend.
Janis
oh, one other thing, I just remembered - I started using a calcium magnesium supplement which has 1000mg magnesium to 500mg calcium, this ratio evidently aids in muscle repair.