Karin -
I used to live in Albuquerque, and spent a lot of time in Santa Fe. What do you like to do? There's wonderful hiking and mountain biking trails. You have fabulous galleries, the Georgia O'Keefe museum, shopping... Taos is an easy drive (about an hour) from Santa Fe, and the Acoma Pueblo (which I highly recommend) is about 2 hours. The food is good, too. Tell me what you like to do, and I can refine this a bit more. I love New Mexico and miss it greatly.