2 words: Muscle confusion. This has happened to me. Power Hour is an endurance workout, lower weight, higher reps. MIS is heavy duty weight-lifitng--do you find you can go heavier on MIS? I can. Also, I think I read somewhere on this forum that the faster and increased number of reps on PowerHour keeps lactic acid from building up in the muscle, so you are less sore. If you do MIS for a while, then go back to PowerHour, I bet you will be sore in a different way. Sorry if I'm rambling.