I'm, obviously, not Cathe, but here are some of my impressions.
Are you talking about the Timesaver DVDs with the Body Blast set? If so, I think it will be challenging for you, but you probably will be able to do them, perhaps initially with some modifications. I just did these DVDs last week for the first time, though I am very familiar with the rest of the Body Blast series.
I think the cardio sections will probably be your toughest challenge. While they aren't long, they do include some of the more intricate step work from workouts like Step Blast and Step Jump and Pump. I would definitely recommend watching the DVDs at least once before doing them because of that.
The weight workouts are pretty standard and if you have been lifting weights regularly for the past 12 weeks, you should be able to do them just fine with whatever weight challenges you. The chest work consists mostly of chest presses/flies, though I believe Cathe may have added push-ups at the end (I just don't remember that for sure right now). But if you can't do those because of your wrist, the presses/flies provide a good workout on their own.
I will say this about workout #5 (the leg workout). I did a five week rotation of the 2006 series in November/December, doing Butts and Guts at least once if not twice a week (I love that workout). I didn't work out for about 10 days due to a vacation, and came back with the Timesavers, just to get my body used to moving again before going into another rotation. The leg workout (which is mostly from Legs and Glutes) kicked my butt! I think it was the high step step-ups, which I hadn't done any of in quite some time. It's a really good leg workout, IMO.
The ab sections are difficult, though if you have been doing abs regularly, I think even if you can't do all of the exercises at first (like the core work on the stability ball that comes from Kick Punch and Crunch), you will probably be able to master them with a little work.
These workouts had a good fun factor for me, but I count the aerobics in Body Blast series as my absolute favorite of Cathe's in terms of fun. I never dread doing a Body Blast aerobic workout and that's a great bonus for me.
Hope you enjoy!