>I experience DOMS after every strength workout (and some
>cardio) and I've been exercising for years (10+). It has more
>to do with how your body handles lactic acid. Everyone has a
>different lactate threshold, mine is particularly low and
>therefore I experience more DOMS than someone with a higher
>threshold. Now, I'm sure that if I did the same workout for
>weeks at a time and never upped my weight I might not
>experience DOMS.
I was reading recently that DOMS most likely (they are not sure) have anything to do with lactic acid (whereas that "burn" during the workout is a sign of lactic acid build-up). It's a sign of microtrauma, but excessive or prolonged DOMS, as you suggest, may be a sign that the micro trauma is becoming MACROtrauma, and the body can't repair it effectively.
I get caught up in the "if it hurts, it works!" mentality regarding DOMS (something that non-exercisers or exercise haters would probably not understand), but I also have read that consuming more antioxidants can reduce DOMS, so it may also depend on what you eat as well.
I rarely get DOMS with Slow and Heavy, even though I really work hard during the workout. On the other hand, endurance workouts like PH give me major DOMS at times. (I especially like DOMS in the glute region!)