Yes.
And no.
What are you after and where are you now? You can tailer your lower body work for the results you want. I do full body workouts that use compound moves that hit everything (one push, one pull, one squat variation... sometimes two of each) and the little 20-30 minute workouts I do now are the most results-getting I've ever done. But I like muscles and my shoulders could probably use some added work so, at some point soon, I'll need to start making changes. But a squat move or two seems to be more than enough to hit EVERYTHING in my lower body without singling out any particular part. An example of tailoring MY workouts: I have naturally thick calves. Even when I was doing marathon body parts sessions I avoided any direct calf work. I felt my calves were getting worked indirectly through all my other standing work and since I didn't want them to get any larger it didn't make sense to directly work them.
Pay attention to how the development of your body progresses. If you feel you have symmetry and are pleased with the strength gains you have, you're golden... for now. But as your body changes and the symmetry starts to fade you will need to fine-tune your workouts, adding and taking away moves that will/won't get you what you're after. If, for instance, you're lower body starts to look underdeveloped next to your upper body, add some compound squat moves for fastest results.