Yes, it does depend on what your nutritional goals are. My nutritional priorities are no sugar of any form, high fiber, lower fat, NO trans fats, and preferably a higher potassium to sodium ratio. The first thing I do when I look at a product is read the ingredients. If sugar or any of its pseudonyms, or trans fat ingredients are anywhere in the list I put it back on the shelf and don't even bother looking the nutritional label. If sugar and trans fats are not in the list, then I look, in this order, at the nutritional label:
1. fiber (if it is a product where fiber is even a potential ingredient).
2. calories per serving (is it a reasonable serving size for the amount of calories?)
3. sodium/potassium ratio. People generally need 3 times as much potassium as sodium, and the two ingredients in balance with each other are important for maintaining healthy blood pressure. Since I don't have blood pressure problems, I don't worry too much about this ratio, but when I see a ratio on a label whereby the potassium outweighs the sodium content, it adds to my conclusion that the food is healthy.
Sandra