I am PLAGUED with HUGE calves (not genetics in my family) and two FigureAthlete.com authors gave me advice.
Dr. Clay Hyght told me to keep doing what I'm doing, especially diet, and they should get smaller. But he also warned that my calf muscles got big and strong carrying around a lot of excess weight for a long time (I was obese for two decades) and that I may only be able to do so much. He said he's seen this many times. So for those of you who are overweight, unless you also want calves that are too large for the rest of you, you might want to drop those pounds sooner rather than later. If I'd known 17" calves might become a permanent condition I know I wouldn't have put off losing weight.
Chad Waterbury said that any time you don't want a muscle group to get bigger that you should never directly work that muscle group. In other words, no calf raises or calf pumps. Inadvertent calf work resulting from squats, lunges, and dead lifts would be unavoidable, however. He also has said a great way to lean-out legs is 20 minutes of steady state running every other day. It's boring, it sucks, but it works.