I'm currently living in Germany, but have lived in many European cities. I think the answer to your question depends upon what kind of a person you are -- do you like to travel? comfortable with change? open to learning a new language (assuming you don't speak French)?
Would you be coming on your own or as a trailing spouse? If the latter, are you okay fending for yourself while your partner works? That often becomes an issue if you've been used to working/having independence and are suddenly dependent.
Do you have your visa arranged or, if moving with a company, do they have a relocation service? With the EU, visas for Americans aren't as easy to come by as they once were given the unemployment rates here.
As for Paris itself, I absolutely love it! Have you visited before? Where some people see charm and history, others find in dirty and overpriced.