We go to Emerald Isle, which is on the southern most Outer Bank, often. My dad lives there. There are a lot of nice houses and condos to rent in the area. I'd recommend picking an island - most are very nice with lots of family things to do - then calling a rental agent in the area. Just a plug for our island - it's very quiet with lots of family entertainment. You cannot park on the streets, so everyone on the beach rents a house or a condo - and the beaches are not crowded. You can rent bikes, kayaks, go to the Pine Knolls Aquarium (which is really nice, actually - not quite the Monterey Bay Aquarium, but not too far off), ride bumper boats, go to a series of water slides (for all ages), fish, crab, boat... And there are a ton of restaurants that range from sandwiches to fine dining. Here's the town website -
http://www.emeraldisle-nc.org/
But where ever you stay - have a great time. I know our kids LOVE it there - even at 16 and 20, it's the one trip were they do not try to ditch us.