A couple months ago I had to up mine from 10mg to 20mg due to major work stress, awful moodswings, and what I think was mild depression brought on by not exercising due to a knee injury. Unfortunately I have experienced weight gain, but I don't know if mine is from not exercising due to the injury or from the medicine. I've gained 15 pounds. However, DH would rather I keep the weight on then go off the meds. They make me a happier/less moody person. I guess I can't blame him for that.