I moved to a naturally desiccated thyroid medication 3 years ago (Armour thyroid, it saved my life.) Synthroid and levothyroxin were making me ill with side effects. Possibly it was just not working and I was having mood swings weight gain depression immense hot flashes insatiable appetite followed by nausea... among other things. Anyhow, things started to get better =) ... but alas my doctor recommended Welbutrin for my depression and moods and added that it may help me quit smoking for good. Just wanted to see if anyone has had any experience with this medication and thyroid disease?... what was your experience?