If you do more than one full body workout a week - then yes. I have been doing a full body rotation to lean out a bit and I had to take an extra rest day. I would agree the High Reps seems to have a challenging leg section. I have learned not to underestimate the energy needed for a full body workout!
when I am training (injured now)...and am doing Cathe's workouts...I generally get my best results by doing her full body workouts (Hi reps. Muscle Max, Muscle End., STS full body,) 3x per week faithfully and only 2x per week if time is tight. I find that is good for my legs...and then I do cardio on the other days that also work the legs...I was very happy with this schedule.