Hi -  I have a slight case of scoliosis.  It was one of the reasons I stopped running.  A lot of my female friends--former runners--had lower disk problems after running for years, so since my spine is slightly askew, I decided not to tempt fate.  Besides, a horrible case of piriformis was the straw that broke that camel's back.  That's another thread.  The bottom line is that I have NO problems doing any of Cathe's tapes.  In fact, doing the PS series and MIS has made my back STRONG---that can only be a good thing.  But that's just me, and my scoliosis is slight.  If yours is more pronounced, I'd check with a good orthopedist (sports medicine type) to make sure.  Good luck.  Suzanna