Hi gettingfitmom! I don't know your genetic blueprint but to some degree the "dimples" are hereditary and stubborn to resist change. But regardless if this is in your genes, you can still improve your situation tremendously by doing both cardio AND weights.....and actually one more, clean eating. The combination of the three will bring the best results you can ask for. You will burn fat, shape your thighs, and keep your system free of processed and high sodium or starch based foods which many times contribute to the dimpling effect. Also, drink lots of water to keep your system cleansed and flushed. Good Luck!