What are the neural tube defects? These defects have a relation with brain and the spinal cord. Two of the main defects are: spina bifida and anencephaly. In these medical conditions, the brain if the fetus does not get enough nutrients and brain do not get properly formed. Those babies who survive may get their left side paralyzed for the whole life. NTDs can be prevented through folic acid pregnancy or if pregnant women start taking the folic acid before conceiving. It is being advised to take 400micrograms of folic acid before pregnancy.